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5-APDI (hydrochloride)

Item No. 13899

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 5-(2-Aminopropyl)-2,3-dihydro-1H-indene
  • IAP
  • Indanylaminopropane
Technical Information
Formal Name
2,3-dihydro-α-methyl-1H-indene-5-ethanamine, monohydrochloride
CAS Number
152623-95-5
Molecular Formula
C12H17N • HCl
Formula Weight
211.7
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMF:PBS(pH 7.2)(1:1): 0.5 mg/mlDMSO: 20 mg/mlEthanol: 10 mg/mlMethanol: 1 mg/ml
λmax
271, 277 nm
SMILES
NC(C)CC1=CC(CCC2)=C2C=C1.Cl
InChi Code
InChI=1S/C12H17N.ClH/c1-9(13)7-10-5-6-11-3-2-4-12(11)8-10;/h5-6,8-9H,2-4,7,13H2,1H3;1H
InChi Key
BYDGFBRMZHXMBV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    5-APDI is an indane with an amphetamine-like aminopropane group. It inhibits the uptake of serotonin, dopamine, and norepinephrine by crude synaptosomes (IC50 = 82, 1,847, and 849 nM, respectively).1 In discrimination studies using rats, 5-APDI fully substitutes for the entactogen N-methyl-1,3-dioxolyl-N-methylbutanamine but does not substitute for amphetamine.1 This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Monte, A.P., Marona-Lewicka, D., Cozzi, N.V., et al. Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogues of 3,4-(methylenedioxy)amphetamine. J. Med. Chem. 36(23), 3700-3706 (1993).