For immunochemical analysis of IκBζ
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IκBζ Polyclonal Antibody

Item No. 13926

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • INAP
  • MAIL
Immunogen
synthetic peptide corresponding to mouse IkBζ amino acids 684-699 and 285-298
Formulation (Request formulation change)
100 µg of protein G-purified IgG in 200 µl PBS, containing 0.2% gelatin and 0.05% sodium azide.
Host
Rabbit
Applications
WB
Specific Activity
amino acids 684-699 and 285-298
Species Reactivity
(+) Mouse IkBζ
Origin
Animal/Rabbit
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    IκBζ is an ankyrin repeat-containing nuclear protein that is highly homologous to the IκB family member Bcl-3. Transcription of IκBζ is upregulated by stimulation with TLR ligands, IL-1, and IL-6 in cultured B-lymphocytes and monocytes/macrophages, but only faintly so in T-lymphocytes, fibroblasts, and endothelial cells. IkBz preferentially associates with the NF-κB subunit p50 rather than p65 and recombinant IκBζ proteins inhibit the DNA binding of the p65/p50 heterodimer and the p50/p50 homodimer.

    WARNING This product is not for human or veterinary use.