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JWH 149

Item No. 13978

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(4-methyl-1-naphthalenyl)(2-methyl-1-pentyl-1H-indol-3-yl)-methanone
CAS Number
548461-82-1
Molecular Formula
C26H27NO
Formula Weight
369.5
Purity
≥95%
Formulation
A 10 mg/ml solution in methanol
Solubility(Learn about Variance in Solubility)
DMF: 16 mg/mlDMSO: 11 mg/mlEthanol: 10 mg/ml
λmax
221, 249, 320 nm
SMILES
O=C(C1=C(C)N(CCCCC)C2=C1C=CC=C2)C3=C(C=CC=C4)C4=C(C)C=C3
InChi Code
InChI=1S/C26H27NO/c1-4-5-10-17-27-19(3)25(23-13-8-9-14-24(23)27)26(28)22-16-15-18(2)20-11-6-7-12-21(20)22/h6-9,11-16H,4-5,10,17H2,1-3H3
InChi Key
JTJAMXUOXJGSCW-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    JWH 149 (Item No. 13978) is a synthetic cannabinoid (CB) which potently binds both the central CB1 receptor (Ki = 5.0 nM) and the peripheral CB2 receptor (Ki = 0.73 nM).1 Its physiological properties have not been elucidated. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Huffman, J.W., Zengin, G., Wu, M.J., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: Steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists. Bioorg. Med. Chem. 13(1), 89-112 (2005).