An Analytical Reference Standard
Features
  • Psilocybin (Item No. 14041) is part of the Cayman Reference Standards™ product line. For a complete list of Cayman Reference Standards™ suitable for analytical testing and research purposes please visit our Forensic Product Search & Drug ID
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Psilocybin

Item No. 14041

Restricted Product (Schedule I)
Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-[2-(dimethylamino)ethyl]-1H-indol-4-ol, 4-(dihydrogen phosphate)
CAS Number
520-52-5
Molecular Formula
C12H17N2O4P
Formula Weight
284.3
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 1 mg/mlPBS (pH 7.2): 2 mg/ml
λmax
222, 268, 290 nm
SMILES
CN(C)CCC1=CNC2=C1C(OP(O)(O)=O)=CC=C2
InChi Code
InChI=1S/C12H17N2O4P/c1-14(2)7-6-9-8-13-10-4-3-5-11(12(9)10)18-19(15,16)17/h3-5,8,13H,6-7H2,1-2H3,(H2,15,16,17)
InChi Key
QVDSEJDULKLHCG-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $85

    Add

    5 mg

    $361

    Add

    10 mg

    $595

    Add

    100 mg

    $3,400

    Add
    Cayman Chemical
    Cayman Spectral Library

    Our free, searchable, GC-MS spectral database contains 70eV EI mass spectral data of 2,000+ of Cayman’s forensic drug standards.

    DOWNLOAD THE DATABASE
    Product Description

    Psilocybin (Item No. 14041) is an analytical reference standard categorized as a tryptamine.1,2 It induces the head-twitch response (HTR) in mice, indicating hallucinogenic potential.2 Psilocybin is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nichols, D.E., and Frescas, S. Improvements to the synthesis of psilocybin and a facile method for preparing the O-acetyl prodrug of psilocin. Synthesis 6, 935-938 (1999).

    2. Glatfelter, G.C., Pottie, E., Partilla, J.S., et al. Structure–activity relationships for psilocybin, baeocystin, aeruginascin, and related analogues to produce pharmacological effects in mice. ACS Pharmacol. Transl. Sci. 5(11), 1181-1196 (2022).

    Product Citations

    Kato, K., Kleinhenz, J.M., Shin, Y.-J., et al. Psilocybin treatment extends cellular lifespan and improves survival of aged mice. NPJ Aging 11(1), 55 (2025).

    Sekssaoui, M., Bockaert, J., Marin, P., et al. Antidepressant-like effects of psychedelics in a chronic despair mouse model: is the 5-HT2A receptor the unique player? Neuropsychopharmacology 49(4), 747-756 (2024).

    Glatfelter, G.C., Pottie, E., Partilla, J.S., et al. Structure–activity relationships for psilocybin, baeocystin, aeruginascin, and related analogues to produce pharmacological effects in mice. ACS Pharmacol. Transl. Sci. 5(11), 1181-1196 (2022).

    Hesselgrave, N., Troppoli, T.A., Wulff, A.B., et al. Harnessing psilocybin: Antidepressant-like behavioral and synaptic actions of psilocybin are independent of 5-HT2R activation in mice. Proc. Natl. Acad. Sci. USA 118(17), e2022489118 (2021).