A methoxylated resveratrol derivative with neuroprotective effects
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Pinostilbene

Item No. 14044

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-[(1E)-2-(4-hydroxyphenyl)ethenyl]-5-methoxy-phenol
CAS Number
42438-89-1
Molecular Formula
C15H14O3
Formula Weight
242.3
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 50 mg/mlEthanol:PBS(pH 7.2) (1:5): 0.15 mg/ml
λmax
218, 307 nm
SMILES
OC1=CC=C(/C=C/C2=CC(OC)=CC(O)=C2)C=C1
InChi Code
InChI=1S/C15H14O3/c1-18-15-9-12(8-14(17)10-15)3-2-11-4-6-13(16)7-5-11/h2-10,16-17H,1H3/b3-2+
InChi Key
KUWZXOMQXYWKBS-NSCUHMNNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $28

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    5 mg

    $118

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    10 mg

    $205

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    25 mg

    $382

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    Product Description

    Pinostilbene is a stable, monomethoxylated resveratrol derivative with enhanced bioavailability compared to resveratrol.1 At 0.1-10 μM pinostilbene reduces neurotoxicity in SH-SY5Y cells induced by the parkinsonian mimetic 6-hydroxydopamine and scavenges 2,2-diphenyl-1-picrylhydrazyl radicals with an IC50 value of 47.1 μM.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wilson, M.A., Rimando, A.M., and Wolkow, C.A. Methoxylation enhances stilbene bioactivity in Caenorhabditis elegans. BMC Pharmacol. 8(15), (2008).

    2. Chao, J., Li, H., Cheng, K.W., et al. Protective effects of pinostilbene, a resveratrol methylated derivative, against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells. J. Nutr. Biochem. 21(6), 482-489 (2010).