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4-acetoxy DMT (hydrochloride)

Item No. 14056

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 4-acetoxy-N,N-Dimethyltryptamine
  • O-Acetylpsilocin
  • Psilacetin
Technical Information
Formal Name
3-[2-(dimethylamino)ethyl]-1H-indol-4-ol-4-acetate, monohydrochloride
CAS Number
2748484-99-1
Molecular Formula
C14H18N2O2 • HCl
Formula Weight
282.8
Purity
≥90%
Formulation
A 10 mg/ml solution in acetonitrile
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 10 mg/mlEthanol: 20 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
219, 277 nm
SMILES
CN(C)CCC1=CNC2=CC=CC(OC(C)=O)=C21.Cl
InChi Code
InChI=1S/C14H18N2O2.ClH/c1-10(17)18-13-6-4-5-12-14(13)11(9-15-12)7-8-16(2)3;/h4-6,9,15H,7-8H2,1-3H3;1H
InChi Key
OEPCTLAWMZJUIX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    4-acetoxy DMT (hydrochloride) (Item No. 14056) is an analytical reference standard categorized as a tryptamine.1,2 4-acetoxy DMT is a prodrug form of psilocin (Item Nos. 9003135 | 11864 | 36971), a psychedelic hallucinogen derived from various mushrooms. 4-acetoxy DMT induces the head-twitch response (HTR) in mice, indicating hallucinogenic potential.2 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nichols, D.E., and Frescas, S. Improvements to the synthesis of psilocybin and a facile method for preparing the O-acetyl prodrug of psilocin. Synthesis 6, 935-938 (1999).

    2. Klein, A.K., Chatha, M., Laskowski, L.J., et al. Investigation of the structure−activity relationships of psilocybin analogues. ACS Pharmacol. Transl. Sci. 4(2), 533-542 (2020).

    Product Citations

    Kozell, L.B., Eshleman, A.J., Swanson, T.L., et al. Pharmacologic activity of substituted tryptamines at 5-HT2AR, 5-HT2CR, 5-HT1AR, and SERT. J. Pharmacol. Exp. Ther. JPET-AR-2022-001454 (2023).

    Gatch, M.B., Hoch, A., and Carbonaro, T.M. Discriminative stimulus effects of substituted tryptamines in rats. ACS Pharmacol. Transl. Sci. 4(2), 467-471 (2020).