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25G-NBOMe (hydrochloride)

Item No. 14065

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,5-dimethoxy-N-[(2-methoxyphenyl)methyl]-3,4-dimethyl-benzeneethanamine, monohydrochloride
CAS Number
1797132-54-7
Molecular Formula
C20H27NO3 • HCl
Formula Weight
365.9
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 3 mg/mlDMSO: 5 mg/mlEthanol: 13 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
279 nm
SMILES
CC1=C(C)C(OC)=CC(CCNCC2=C(OC)C=CC=C2)=C1OC.Cl
InChi Code
InChI=1S/C20H27NO3.ClH/c1-14-15(2)20(24-5)16(12-19(14)23-4)10-11-21-13-17-8-6-7-9-18(17)22-3;/h6-9,12,21H,10-11,13H2,1-5H3;1H
InChi Key
JIXRXNLCFFXKOZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    25G-NBOMe (hydrochloride) is a derivative of 2C-G, characterized by the addition of a benzyl-methoxy (BOMe) group to the amine.1 While the properties of this compound are not known, the N-(2-methoxybenzyl) addition significantly increases the affinity and activity of other disubstituted phenethylamines at the 5-HT2A serotonin receptor.2,3 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zuba, D., and Sekula, K. Analytical characterization of three hallucinogenic N-(2-methoxy)benzyl derivatives of the 2C-series of phenethylamine drugs. Drug Test. Anal. (2012).

    2. Braden, M.R., Parrish, J.C., Naylor, J.C., et al. Molecular interaction of serotonin 5-HT2A receptor residues Phe3396.51 and Phe3406.52 with superpotent N-benzyl phenethylamine agonists. Mol. Pharm. 70(6), 1956-1965 (2006).

    3. Ettrup, A., Palner, M., Gillings, N., et al. Radiosysnthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET. J. Nucl. Med. 51(11), 1763-1770 (2010).