An inhibitor of eukaryotic protein synthesis
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Enantiomer(s)
13998(−)-Methamphetamine (hydrochloride)
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Cycloheximide

Item No. 14126

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-2,6-piperidinedione
CAS Number
66-81-9
Synonyms
  • Naramycin A
  • NSC 185
Molecular Formula
C15H23NO4
Formula Weight
281.4
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 25 mg/mlEthanol: 25 mg/mlWater: 20 mg/ml
SMILES
O=C1[C@@]([C@H](O)CC2CC(NC(C2)=O)=O)([H])C[C@@H](C)C[C@@H]1C
InChi Code
InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1
InChi Key
YPHMISFOHDHNIV-FSZOTQKASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 mg

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    Cayman Chemical
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    Product Description

    Cycloheximide is a glutarimide antibiotic produced by S. griseus that inhibits protein synthesis in eukaryotes (IC50 = 5-50 μM) by interfering with translational elongation.1 Its effects on protein synthesis can either induce or inhibit apoptosis depending on cell type.2 Cycloheximide is widely used as a tool in molecular biology research for ribosome profiling and translational profiling as well as to determine the half-life of a protein.3,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
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