An Analytical Reference Standard
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Certified Reference Material(s)
40336Fenethylline (hydrochloride) (CRM)
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Fenethylline (hydrochloride)

Item No. 14146

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Amphetaminoethyltheophylline
  • Amfetyline
  • NSC 169872
Technical Information
Formal Name
3,7-dihydro-1,3-dimethyl-7-[2-[(1-methyl-2-phenylethyl)amino]ethyl]-1H-purine-2,6-dione, monohydrochloride
CAS Number
1892-80-4
Molecular Formula
C18H23N5O2 • HCl
Formula Weight
377.9
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 0.3 mg/mlDMSO: 0.5 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
275 nm
SMILES
CN1C(N(C)C(N=CN2CCNC(C)CC3=CC=CC=C3)=C2C1=O)=O.Cl
InChi Code
InChI=1S/C18H23N5O2.ClH/c1-13(11-14-7-5-4-6-8-14)19-9-10-23-12-20-16-15(23)17(24)22(3)18(25)21(16)2;/h4-8,12-13,19H,9-11H2,1-3H3;1H
InChi Key
MVXGSLGVWBVZCA-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Fenethylline (hydrochloride) (Item No. 14146) is an analytical reference standard categorized as a stimulant.1,2 Fenethylline is a theophylline derivative of amphetamine. It has been found in tablets seized by authorities.1 Formulations containing fenethylline have been used in the treatment of attention-deficit/hyperactivity disorder (ADHD) and narcolepsy. Fenethylline is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Katselou, M., Papoutsis, I., Nikolaou, P., et al. Fenethylline (captagon) abuse - local problems from an old drug become universal. Basic Clin. Pharmacol. Toxicol. 119(2), 133-140 (2016).

    2. Kristen, G., Schaefer, A., and von Schlichtegroll, A. Fenetylline: Therapeutic use, misuse and/or abuse. Drug Alcohol Depend. 17(2-3), 259-271 (1986).