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(±)-β-Hydroxybutyrate

Item № 14148
CAS № 300-85-6
Purity ≥95%
product image
                (CAS 300-85-6)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 g $38.00 0.00
     5 g $133.00 0.00
     10 g $247.00 0.00

Pricing updated 2019-03-24. Prices are subject to change without notice.

Description
Synonyms
  • 3-Hydroxybutyric Acid
  • NSC 3806
  • βOHB

(±)-β-Hydroxybutyrate (βOHB) is an endogenous and specific inhibitor of class I histone deacetylases (HDACs), increasing acetylation of histones in a dose-dependent manner.1 It does not increase acetylation of α-tubulin, indicating that it does not inhibit the class IIb HDAC6.1 Fasting or caloric restriction, two conditions associated with increased βOHB abundance, increases global histone acetylation in mouse tissues.1

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Technical Information
Formal Name
3-hydroxy-butanoic acid
CAS Number
300-85-6
Synonyms
  • 3-Hydroxybutyric Acid
  • NSC 3806
  • βOHB
Molecular Formula
C4H8O3
Formula Weight
104.1
Purity
≥95%
Formulation
A liquid or solid
λmax
210 nm
SMILES
CC(O)CC(O)=O
InChI Code
InChI=1S/C4H8O3/c1-3(5)2-4(6)7/h3,5H,2H2,1H3,(H,6,7)/t3-/m
InChI Key
WHBMMWSBFZVSSR-UHFFFAOYSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
Downloads & Resources
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Download Safety Data Sheet (SDS)

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Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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References & Product Citations
Product Description References

1. Shimazu, T., Hirschey, M.D., Newman, J., et al. Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor Science 339, 211-214 (2013).

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