Induces stem cell differentiation
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

KY 02111

Item No. 14315

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(6-chloro-2-benzothiazolyl)-3,4-dimethoxy-benzenepropanamide
CAS Number
1118807-13-8
Molecular Formula
C18H17ClN2O3S
Formula Weight
376.9
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 10 mg/ml
λmax
204, 223, 281, 304 nm
SMILES
ClC1=CC=C2C(SC(NC(CCC3=CC=C(OC)C(OC)=C3)=O)=N2)=C1
InChi Code
InChI=1S/C18H17ClN2O3S/c1-23-14-7-3-11(9-15(14)24-2)4-8-17(22)21-18-20-13-6-5-12(19)10-16(13)25-18/h3,5-7,9-10H,4,8H2,1-2H3,(H,20,21,22)
InChi Key
LXFKEVQQSKQXPR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $75

    Add

    10 mg

    $143

    Add

    25 mg

    $278

    Add

    50 mg

    $510

    Add
    Product Description

    KY 02111 promotes the differentiation of human pluripotent stem cells to cardiomyocytes by inhibiting Wnt signaling.1 Treatment with 10 μM of KY 02111 has been shown to increase the ratio of beating cardiac colonies by 70–94% in cell aggregates of the embryonic stem cell lines KhES-1 and KhES-3 as well as the induced pluripotent stem cell lines 253G1, IMR90-1, IMR90-4, and RCHIPC0003.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Minami, I., Yamada, K., Otsuji, T.G., et al. A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions. Cell Rep. 2(5), 1448-1460 (2012).