A non-denaturing detergent
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Biochemicals
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n-Octylglucoside

Item No. 14327

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
octyl-β-D-glucopyranoside
CAS Number
29836-26-8
Synonyms
  • BTB 11967
Molecular Formula
C14H28O6
Formula Weight
292.4
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 16 mg/mlDMSO: 16 mg/mlEthanol: 20 mg/mlPBS (pH 7.2): 5 mg/ml
SMILES
O[C@@H]1[C@@H](O)[C@H](OCCCCCCCC)O[C@H](CO)[C@H]1O
InChi Code
InChI=1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1
InChi Key
HEGSGKPQLMEBJL-RKQHYHRCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

    $49

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    5 g

    $178

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    10 g

    $329

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    Product Description

    n-Octylglucoside is a mild, non-denaturing detergent that is used for the solubilization and reconstitution of membrane-bound proteins. The high critical micelle concentration (0.7%) of n-octylglucoside facilitates ready removal from final protein extracts by dialysis or gel filtration.1,2 n-Octylglucoside can be used in 2D electrophoresis and to improve selectivity of immunoprecipitation of phosphotyrosine modified proteins.3,1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhang, G., and Neubert, T.A. Use of detergents to increase selectivity of immunoprecipitation of tyrosine phosphorylated peptides prior to identification by MALDI quadrupole-TOF MS. Proteomics 6(2), 571-578 (2006).

    2. Petri, W.A., Jr., and Wagner, R.R. Reconstitution into liposomes of the glycoprotein of vesicular stomatitis virus by detergent dialysis. The Journal of Biological Chemisty 254(11), 4313-4316 (1979).

    3. Lambot, M., Frétier, S., Op De Beeck, A., et al. Reconstitution of hepatitis C virus envelope glycoproteins into liposomes as a surrogate model to study virus attachment. The Journal of Biological Chemisty 277(23), 20625-20630 (2002).