A prodrug for 8-iso PGE2
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8-iso Prostaglandin E2 isopropyl ester

Item No. 14352

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(8β)-11,15S-dihydroxy-9-oxo-prosta-5Z,13E-dien-1-oic acid, 1-methylethyl ester
CAS Number
330589-21-4
Synonyms
  • 8-iso PGE2 isopropyl ester
Molecular Formula
C23H38O5
Formula Weight
394.6
Purity
≥98%
Formulation (Request formulation change)
A 1 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: >30 mg/mlDMSO: >50 mg/mlEthanol: >50 mg/mlPBS (pH 7.2): <50 µg/ml
SMILES
O=C1[C@@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1
InChi Code
InChI=1S/C23H38O5/c1-4-5-8-11-18(24)14-15-20-19(21(25)16-22(20)26)12-9-6-7-10-13-23(27)28-17(2)3/h6,9,14-15,17-20,22,24,26H,4-5,7-8,10-13,16H2,1-3H3/b9-6-,15-14+/t18-,19-,20+,22+/m0/s1
InChi Key
NOHLKSJQMSPOTB-YRLDPNHWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    8-iso Prostaglandin E2 isopropyl ester (8-iso PGE2 isopropyl ester) is a more lipophilic form of the free acid, 8-iso PGE2. Prostaglandin esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of prostaglandins show greatly diminished agonist activity in vitro compared to the parent free acids.

    WARNING This product is not for human or veterinary use.