An Analytical Reference Standard
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Unlabeled Version(s)
14228JWH 203 N-(5-hydroxypentyl) metabolite
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JWH 203 N-(5-hydroxypentyl) metabolite-d5

Item No. 14368

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(2-chlorophenyl)-1-(1-(5-hydroxypentyl)-1H-indol-3-yl-2,4,5,6,7-d5)ethan-1-one
CAS Number
2748335-77-3
Molecular Formula
C21H17D5ClNO2
Formula Weight
360.9
Purity
≥99% deuterated forms (d1-d5)
Formulation
A solution in acetonitrile
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 5 mg/ml
λmax
215, 245, 300 nm
SMILES
O=C(CC1=C(Cl)C=CC=C1)C2=C([2H])N(CCCCCO)C3=C2C([2H])=C([2H])C([2H])=C3[2H]
InChi Code
InChI=1S/C21H22ClNO2/c22-19-10-4-2-8-16(19)14-21(25)18-15-23(12-6-1-7-13-24)20-11-5-3-9-17(18)20/h2-5,8-11,15,24H,1,6-7,12-14H2/i3D,5D,9D,11D,15D
InChi Key
RFHPYWJZEUWQOM-JFISFECYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    JWH 203 N-(5-hydroxypentyl) metabolite-d5 (Item No. 14368) is intended for use as an internal standard for the quantification of JWH 203 N-(5-hydroxypentyl) metabolite (Item No. 14228) by GC- or LC-mass spectrometry. JWH 203 is an analgesic chemical from the phenylacetylindole family that acts as a cannabinoid (CB) agonist with Ki values of 8.0 and 7.0 nM at the central (CB1) and peripheral (CB2) receptors, respectively.1 Similar to the related 2'-methoxy compound JWH 250 (Item No. 13634), JWH 203 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole CB compounds. Compared to JWH 250, JWH 203 displays slightly more potent binding affinities for the CB1 and CB2 CB receptors (JWH 250 Kis = 11 and 33 nM, respectively).1 JWH 203 N-(5-hydroxypentyl) metabolite is expected to be a metabolite of JWH 203 that would be detectable both in serum and in urine. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Huffman, J.W., Szklennik, P.V., Almond, A., et al. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg. Med. Chem. Lett. 15(18), 4110-4113 (2005).