A phosphodiesterase inhibitor
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Obscurolide A1

Item No. 14439

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[[tetrahydro-2-(3-hydroxy-1-butenyl)-5-oxo-3-furanyl]amino]-benzoic acid
CAS Number
144397-99-9
Molecular Formula
C15H17NO5
Formula Weight
291.3
Purity
≥98%
Formulation
A solid
SMILES
O=C(O)C1=CC=C(NC2C(/C=C/C(C)O)OC(C2)=O)C=C1
InChi Code
InChI=1S/C15H17NO5/c1-9(17)2-7-13-12(8-14(18)21-13)16-11-5-3-10(4-6-11)15(19)20/h2-7,9,12-13,16-17H,8H2,1H3,(H,19,20)/b7-2+
InChi Key
IZSWILLJDXDGDJ-FARCUNLSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    1 mg

    $117

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    5 mg

    $484

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    Product Description

    Obscurolide A1 is a natural butyrolactone isolated from S. viridochromogenes.1 It inhibits calcium/calmodulin-dependent phosphodiesterase from bovine brain, presumably PDE1 (IC50 = 15 mM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hoff, H., Drautz, H., Fiedler, H.P., et al. Metabolic products of microorganisms. 261. Obscurolides, a novel class of phosphodiesterase inhibitors from streptomyces. I. Production, isolation, structural elucidation and biological activity of obscurolides A1 to A4. J. Antibiot. (Tokyo) 45(7), 1096-1107 (1992).