An inhibitor of specific serine proteases
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Trypsin Inhibitor (soybean)

Item No. 14502

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
9035-81-8
Synonyms
  • Kunitz Trypsin Inhibitor
  • MR 20
  • SBTI
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 1 mg/mlWater: 1 mg/ml
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

    $54

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    100 mg

    $91

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    250 mg

    $190

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    Product Description

    Trypsin inhibitor (soybean) is an inhibitor of serine proteases first isolated and characterized by Kunitz.1 It dose-dependently inhibits trypsin from a variety of sources, as well as plasma kallikrein, thrombin, plasmin, and other serine proteases.1,2,3,4 Trypsin inhibitor (soybean) also partially inhibits chymotrypsin and neutrophil elastase.1,5

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kunitz, M. Crystalline soybean trypsin inhibitor: II. General properties. J. Gen. Physiol. 30(4), 291-310 (1947).

    2. Harpel, P.C. Human plasma alpha 2-macroglobulin. An inhibitor of plasma kallikrein. J. Exp. Med. 132(2), 329-352 (1970).

    3. Lanchantin, G.F., Friedmann, J.A., and Hart, D.W. Interaction of soybean trypsin inhibitor with thrombin and its effect on prothrombin activation. The Journal of Biological Chemisty 244(3), 865-875 (1969).

    4. Feeney, R.E., Means, G.E., and Bigler, J.C. Inhibition of human trypsin, plasmin, and thrombin by naturally occurring inhibitors of proteolytic enzymes. The Journal of Biological Chemisty 244(8), 1957-1960 (1969).

    5. Ribeiro, J.K., Cunha, D.D., Fook, J.M., et al. New properties of the soybean trypsin inhibitor: Inhibition of human neutrophil elastase and its effect on acute pulmonary injury. Eur. J. Pharmacol. 644(1-3), 238-244 (2010).