A stable, synthetic PGE2 analog and powerful bronchoconstrictor
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11-deoxy Prostaglandin E2

Item No. 14520

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
15S-hydroxy-9-oxo-prosta-5Z,13E-dien-1-oic acid
CAS Number
35536-53-9
Synonyms
  • 11-deoxy PGE2
Molecular Formula
C20H32O4
Formula Weight
336.5
Purity
≥99%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: >100 mg/mlDMSO: >100 mg/mlEthanol: >100 mg/mlPBS (pH 7.2): >5 mg/ml
SMILES
CCCCC[C@H](O)/C=C/[C@H]([C@H]1C/C=C\CCCC(O)=O)CCC1=O
InChi Code
InChI=1S/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h4,7,12,14,16-18,21H,2-3,5-6,8-11,13,15H2,1H3,(H,23,24)/b7-4-,14-12+/t16-,17-,18+/m0/s1
InChi Key
CTHZICXYLKQMKI-FOSBLDSVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    5 mg

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    10 mg

    $547

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    Product Description

    11-deoxy Prostaglandin E2 (11-deoxy PGE2) is a stable, synthetic analog of PGE2 (Item No. 14010). In contrast to PGE2 which has bronchodilation effects, 11-deoxy PGE2 is a powerful bronchoconstrictor and contracts human respiratory tract smooth muscle with potencies ranging from 5 to 30 times higher than PGF2α (Item No. 16010).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Karim, S.M.M., Adaikan, P.G., and Kottegoda, S.R. Prostaglandins and human respiratory tract smooth muscle: Structure activity relationship. Adv. Prostaglandin Thromboxane Res. 7, 969-980 (1980).