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JWH 018 N-propanoic acid metabolite

Item No. 14646

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • AM2201 N-propanoic acid metabolite
  • JWH 073 N-propanoic acid metabolite
Technical Information
Formal Name
3-(1-naphthalenylcarbonyl)-1H-indole-1-propanoic acid
CAS Number
1451369-32-6
Molecular Formula
C22H17NO3
Formula Weight
343.4
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlEthanol: 10 mg/mlMethanol: 30 mg/ml
λmax
218, 245, 313 nm
SMILES
O=C(C1=CC=CC2=C1C=CC=C2)C3=CN(CCC(O)=O)C4=C3C=CC=C4
InChi Code
InChI=1S/C22H17NO3/c24-21(25)12-13-23-14-19(17-9-3-4-11-20(17)23)22(26)18-10-5-7-15-6-1-2-8-16(15)18/h1-11,14H,12-13H2,(H,24,25)
InChi Key
VCRZMEAJRGIGCT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    JWH 018 (Item No. 10900) is a mildly selective agonist of peripheral cannabinoid (CB2) receptor, derived from the aminoalkylindole WIN 55,212-2. JWH 018 binds central cannabinoid (CB1) and CB2 receptors with Ki values of 9.0 and 2.94 nM, respectively.1 JWH 018 is one of several synthetic CBs that have been included in smoking mixtures.2 JWH 018 N-propanoic acid metabolite (Item No. 14646) is a major metabolite of JWH 018 that is detectable in urine.2 The biological and toxicological properties of this compound have not been characterized. This analytical reference standard is intended for forensic and research applications only.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend. 60(2), 133-140 (2000).

    2. Lovett, D.P., Yanes, E.G., Herbelin, T.W., et al. Structure elucidation and identification of a common metabolite for naphthoylindole-based synthetic cannabinoids using LC-TOF and comparison to a synthetic reference standard. Forensic Sci. Int. 226(1-3), 81-87 (2013).