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α-Ethyltryptamine

Item No. 14653

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • α-ET
  • 3-Indolybutylamine
  • NSC 88061
  • Ro 3-1932
Technical Information
Formal Name
α-ethyl-1H-indole-3-ethanamine
CAS Number
2235-90-7
Molecular Formula
C12H16N2
Formula Weight
188.3
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 11 mg/mlDMSO: 5 mg/mlEthanol: 20 mg/mlEthanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
λmax
222, 282 nm
SMILES
NC(CC)CC1=CNC2=CC=CC=C21
InChi Code
InChI=1S/C12H16N2/c1-2-10(13)7-9-8-14-12-6-4-3-5-11(9)12/h3-6,8,10,14H,2,7,13H2,1H3
InChi Key
ZXUMUPVQYAFTLF-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

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    Product Description

    α-Ethyltryptamine (α-ET) is a tryptamine derivative with schedule 1 status in the United States.1,2 It has been reported to be a potent releaser of serotonin, norepinephrine, and dopamine as well as an inhibitor of monoamine oxidase.3,4 In tests of stimulus generalization in rats, α-ET generalized to DOM (Item No. 11145) and PMMA (Item No. 11562) with ED50 values of 0.4 and 0.7 mg/kg, respectively.3 This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gey, K.F., and Pletscher, A. Effect of α-alkylated tryptamine derivatives on 5-hydroxytryptamine metabolism in vivo. Br. J. Pharmacol. Chemother. 19(1), 161-167 (1962).

    2. Nagai, F., Nonaka, R., and Satoh Hisashi Kamimura, K. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain. Eur. J. Pharmacol. 559(2-3), 132-137 (2007).

    3. Glennon, R.A., Bondareva, T., and Young, R. α-Ethyltryptamine (α-ET) as a discriminative stimulus in rats. Pharmacol. Biochem. Behav. 85(2), 448-453 (2006).

    4. Martinez, D.L., and Geyer, M.A. Characterization of the disruptions of prepulse inhibition and habituation of startle induced by α-ethyltryptamine. Neuropsychopharmacology 16(3), 246-255 (1997).