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JWH 081-N-(cyclohexylmethyl) analog

Item № 14655
CAS № 1373876-34-6
Purity ≥98%
product image
                (CAS 1373876-34-6)

Formulation:  A crystalline solid

SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 mg $65.00 0.00
     5 mg $293.00 0.00
     10 mg $520.00 0.00

Pricing updated 2019-05-25. Prices are subject to change without notice.

Description

JWH 081 (Item No. 10579) is a cannabimimetic aminoalkylindole that shows a high-affinity for the central cannabinoid (CB1) receptor with a Ki value of 1.2 nM and ten-fold reduced affinity for the peripheral cannabinoid (CB2) receptor (Ki = 12.4 nM).1,2 JWH 081-N-(cyclohexylmethyl) analog is a synthetic CB where a cyclohexylmethyl group replaces the alkyl group of the parent compound. The physiological and toxicological properties of this compound are unknown. This product is intended for forensic and research purposes.

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Technical Information
Formal Name
[1-(cyclohexylmethyl)-1H-indol-3-yl](4-methoxy-1-naphthalenyl)-methanone
CAS Number
1373876-34-6
Molecular Formula
C27H27NO2
Formula Weight
397.5
Purity
≥98%
Formulation
A crystalline solid
λmax
213, 319 nm
SMILES
O=C(C1=CC=C(OC)C2=C1C=CC=C2)C3=CN(CC4CCCCC4)C5=C3C=CC=C5
InChI Code
InChI=1S/C27H27NO2/c1-30-26-16-15-23(20-11-5-6-13-22(20)26)27(29)24-18-28(17-19-9-3-2-4-10-19)25-14-8-7-12-21(24)25/h5-8,11-16,18-19H,2-4,9-10,17H2,1H3
InChI Key
LMENRXZOUBANKQ-UHFFFAOYSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding Drug Alcohol Depend. 60(2), 133-140 (2000).

2. Huffman, J.W., Zengin, G., Wu, M.J., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: Steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists Bioorg. Med. Chem. 13, 89-112 (2005).

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