17-phenyl trinor Prostaglandin E2
Item № 14810
CAS № 38315-43-4
Purity ≥98%
500 µg $33.00 $0.00
1 mg $63.00 $0.00
5 mg $264.00 $0.00
10 mg $462.00 $0.00

Pricing updated 2016-05-24. Prices are subject to change without notice.

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  • 17-phenyl trinor PGE2

17-phenyl trinor PGE2 is a synthetic analog of PGE2. It is an EP1 and EP3 receptor agonist.1,2 17-phenyl trinor PGE2 causes contraction of the guinea pig ileum at a concentration of 11 µM.1 It is slightly less potent than PGE2 in stimulating gerbil colon and rat uterus.2 With an ED50 value of 350 µg/kg, 17-phenyl trinor PGE2 is 4.4 times more potent than PGE2 as an antifertility agent in hamsters.2

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Technical Information
Formal Name 9-oxo-11α,15S-dihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid
CAS Number 38315-43-4
  • 17-phenyl trinor PGE2
Molecular Formula C23H30O5
Formula Weight 386.5
Purity ≥98%
Formulation A crystalline solid
SMILES O[C@H]1[C@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@@H](C/C=C\CCCC(O)=O)C(C1)=O
InChI Code 1S/C23H30O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,14-15,18-20,22,24,26H,2,7,10-13,16H2,(H,27,28)/b6-1-,15-14+/t18-,19+,20+,22+/m0/s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Stability As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
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References & Background Reading
Product Description References

1. Lawrence, R.A., Jones, R.L., and Wilson, N.H. Characterization of receptors involved in the direct and indirect actions of prostaglandins E and I on the guinea-pig ileum. Br J Pharmacol 105 271-278 (1992).

2. Miller, W.L., Weeks, J.R., Lauderdale, J.W., et al. Biological activities of 17-phenyl-18,19,20-trinorprostaglandins. Prostaglandins 9 9-18 (1975).

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