A cephalosporin antibiotic
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Ceftazidime (hydrate)

Item No. 14828

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-pyridinium, pentahydrate
CAS Number
78439-06-2
Molecular Formula
C22H22N6O7S2 • 5H2O
Formula Weight
636.7
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 5 mg/ml
SMILES
O=C(C1NC(/C(C2=CSC(N)=N2)=N\OC(C)(C)C(O)=O)=O)N3[C@]1([H])SCC(C[N+]4=CC=CC=C4)=C3C([O-])=O.O.O.O.O.O
InChi Code
InChI=1S/C22H22N6O7S2.5H2O/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27;;;;;/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34);5*1H2/b26-13-;;;;;/t14?,18-;;;;;/m1...../s1
InChi Key
NMVPEQXCMGEDNH-IPHVXHCQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 mg

    $80

    Add

    1 g

    $119

    Add

    5 g

    $389

    Add

    10 g

    $622

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    Ceftazidime is a cephalosporin antibiotic.1 It is active against isolates of numerous Gram-positive and Gram-negative bacteria, including E. coli, K. pneumoniae, P. mirabilis, and S. pyogenes (MICs = 0.015-8 µg/ml for all). It binds to E. coli penicillin-binding protein 1a (PBP1a), -1b, -2, and -3 (IC50s = 0.9, 3.4, 240, and 0.06 µg/ml, respectively).2 Ceftazidime increases survival in mice infected with strains of S. aureus, E. coli, K. pneumoniae, Proteus, or Serratia (ED50s = 0.1-25 mg/kg for all).1 Formulations containing ceftazidime have been used in the treatment of bacterial infections.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Acred, P., Ryan, D.M., Sowa, M.A., et al. The in-vivo antibacterial activity of ceftazidime (Gr 20263)—a comparison with other new β-lactam antibiotics and gentamicin. J. Antimicrob. Chemother. 8(Suppl. B), 247-255 (1981).

    2. Fontana, R., Cornaglia, G., Ligozzi, M., et al. The final goal: Penicillin-binding proteins and the target of cephalosporins. Clin. Microbiol. Infect. 6(Suppl. 3), 34-40 (2000).