A spin trap
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BMPO

Item No. 14958

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3,4-dihydro-2-methyl-1,1-dimethylethyl ester-2H-pyrrole-2-carboxylic acid-1-oxide
CAS Number
387334-31-8
Synonyms
  • BocMPO
Molecular Formula
C10H17NO3
Formula Weight
199.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 25 mg/mlEthanol: 33 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
239 nm
SMILES
[O-][N+]1=CCCC1(C)C(OC(C)(C)C)=O
InChi Code
InChI=1S/C10H17NO3/c1-9(2,3)14-8(12)10(4)6-5-7-11(10)13/h7H,5-6H2,1-4H3
InChi Key
MDMUYJRRYYXDLZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $132

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    10 mg

    $185

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    25 mg

    $393

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    50 mg

    $655

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    Product Description

    BMPO is a cyclic nitrone spin trap that can be used for the detection and characterization of thiyl radicals, hydroxyl radicals, and superoxide anions in vitro or in vivo.1 The BMPO-superoxide adduct does not rapidly decompose to the hydroxyl adduct in cells (t½ = 23 min).1,2 Also, the ESR spectrum of the BMPO-glutathionyl adduct does not fully overlap with the spectrum of its hydroxyl adduct.1 Purified by crystallization and stored as a solid, BMPO has a longer shelf life than liquid spin traps.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhao, H., Joseph, J., Zhang, H., et al. Synthesis and biochemical applications of a solid cyclic nitrone spin trap: A relatively superior trap for detecting superoxide anions and glutathiyl radicals. Free Radic. Biol. Med. 31(5), 599-606 (2001).

    2. Khan, N., Wilmont, C.M., Rosen, G.M., et al. Spin traps: In vitro toxicity and stability of radical adducts. Free Radic. Biol. Med. 34(11), 1473-1481 (2003).