A medium-chain acylcarnitine
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Octanoyl-DL-carnitine (chloride)

Item No. 15048

Technical Information
Formal Name
3-carboxy-N,N,N-trimethyl-2-[(1-oxooctyl)oxy]-1-propanaminium, monochloride
CAS Number
14919-35-8
Synonyms
  • CAR 8:0
  • C8:0 Carnitine
  • DL-Carnitine octanoyl ester
  • (±)-Octanoylcarnitine
  • DL-Octanoylcarnitine
Molecular Formula
C15H30NO4 • Cl
Formula Weight
Purity
≥98%
A crystalline solid
DMF: 20 mg/mlDMSO: 10 mg/mlEthanol: 20 mg/ml
SMILES
OC(CC(C[N+](C)(C)C)OC(CCCCCCC)=O)=O.[Cl-]
InChi Code
InChI=1S/C15H29NO4.ClH/c1-5-6-7-8-9-10-15(19)20-13(11-14(17)18)12-16(2,3)4;/h13H,5-12H2,1-4H3;1H
InChi Key
MYMFUYYXIJGKKU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Octanoyl-DL-carnitine is a medium-chain acylcarnitine. It decreases the oxidation rate of the branched-chain 2-oxo acids 3-methyl-2-butanoate and 4-methyl-2-oxopentanoate in isolated rat muscle mitochondria in the presence of carnitine, but increases it in the absence of carnitine.1 Octanoyl-DL-carnitine, with malate, has been used as a mitochondrial respiration substrate to measure the effect of creatine on the respiration rate of isolated rat cardiac fibers exposed to increasing concentrations of ADP.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Veerkamp, J.H., van Moerkerk, H.T.B., and Wagenmakers, A.J.M. Interaction of short-chain and branched-chain fatty acids and their carnitine and CoA esters and of various metabolites and agents with branced-chain 2-oxo acid oxidation in rat muscle and liver mitochondria. Int. J. Biochem. 17(9), 967-974 (1985).

    2. Toleikis, A., Trumbeckaite, S., Liobikas, J., et alFatty acid oxidation and mitochondrial morphology changes as key modulators of the affinity for ADP in rat heart mitochondria. Cells 9(2), 340 (2020).