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JWH 018 benzimidazole analog

Item No. 15074

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • BIM-018
Technical Information
Formal Name
naphthalen-1-yl(1-pentyl-1H-benzo[d]imidazol-2-yl)methanone
CAS Number
2316839-70-8
Molecular Formula
C23H22N2O
Formula Weight
342.4
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlEthanol: 10 mg/mlMethanol: 30 mg/ml
λmax
219, 324 nm
SMILES
O=C(C1=C(C=CC=C2)C2=CC=C1)C3=NC4=C(C=CC=C4)N3CCCCC
InChi Code
InChI=1S/C23H22N2O/c1-2-3-8-16-25-21-15-7-6-14-20(21)24-23(25)22(26)19-13-9-11-17-10-4-5-12-18(17)19/h4-7,9-15H,2-3,8,16H2,1H3
InChi Key
ZJWSSWFQIOEVCU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    JWH 018 (Item No. 10900) is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor with Ki values of 9.0 and 2.94 nM for the central cannabinoid (CB1) and CB2 receptors, respectively.1 JWH 018 benzimidazole analog replaces the indole core of JWH 018 with a benzimidazole core. While the physiological and toxicological properties of this compound have not been tested, other benzimidazole derivatives demonstrate high selectivity for the CB2 receptor.2 This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend. 60(2), 133-140 (2000).

    2. Pagé, D., Balaux, E., Boisvert, L., et al. Novel benzimidazole derivatives as selective CB2 agonists. Bioorg. Med. Chem. Lett. 18(13), 3695-3700 (2008).