A cationic phosphocholine
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1,2-Dipalmitoyl-sn-glycero-3-EPC (chloride)

Item No. 15099

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-ethoxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacosan-1-aminium, 4-oxide, monochloride
CAS Number
328250-18-6
Synonyms
  • 1,2-Dipalmitoyl-sn-glycero-3-Ethylphosphocholine
  • DPEPC
  • EDPPC
  • 16:1-EPC
Molecular Formula
C42H85NO8P • Cl
Formula Weight
798.6
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Chloroform: 10 mg/mlEthanol: 25 mg/ml
SMILES
O=C(CCCCCCCCCCCCCCC)OC[C@@H](OC(CCCCCCCCCCCCCCC)=O)COP(OCC[N+](C)(C)C)(OCC)=O.[Cl-]
InChi Code
InChI=1S/C42H85NO8P.ClH/c1-7-10-12-14-16-18-20-22-24-26-28-30-32-34-41(44)47-38-40(39-50-52(46,48-9-3)49-37-36-43(4,5)6)51-42(45)35-33-31-29-27-25-23-21-19-17-15-13-11-8-2;/h40H,7-39H2,1-6H3;1H/q+1;/p-1/t40-,52?;/m1./s1
InChi Key
XXTKXMLARLHZSM-WGVGMMHHSA-M
Side Chain Carbon Sum
32:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $54

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    10 mg

    $103

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    25 mg

    $216

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    100 mg

    $539

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    Product Description

    1,2-Dipalmitoyl-sn-glycero-3-EPC is a phospholipid containing the saturated long-chain (16:0) stearic acid inserted at the sn-1 and sn-2 positions and an alkyl group on the phosphate oxygen of the polar headgroup. Cationic phospholipids such as this have proved useful as DNA transfection agents and for studies of surface charge density within lipid bilayers.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lewis, R.N., Winter, I., Kriechbaum, M., et al. Studies of the structure and organization of cationic lipid bilayer membranes: Calorimetric, spectroscopic, and x-ray diffraction studies of linear saturated P-O-ethyl phosphatidylcholines. Biophys. J. 80(3), 1329-1342 (2001).

    2. Heath, G.R., Johnson, B.R., Olmsted, P.D., et al. Actin assembly at model-supported lipid bilayers. Biophys. J. 105(10), 2355-2365 (2013).