2,3-dinor-6-keto Prostaglandin F1α (sodium salt) | Cayman Chemical
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2,3-dinor-6-keto Prostaglandin F (sodium salt)

Item № 15120
Purity ≥95%
product image
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     100 µg $29.00 0.00
     500 µg $131.00 0.00
     1 mg $232.00 0.00
     5 mg $1,015.00 0.00

Pricing updated 2018-11-16. Prices are subject to change without notice.

Description
Synonyms
  • 2,3-dinor-6-keto PGF (sodium salt)

2,3-dinor-6-keto prostaglandin F (2,3-dinor-6-keto PGF) is the β-oxidation product of 6-keto PGF and the major urinary metabolite of PGI2 in humans.1,2 2,3-dinor-6-keto PGF makes up 23% of the recovered radioactivity in urine after administration of labeled 6-keto PGF and 20.5% after administration of labeled PGI2.2 In healthy human subjects, the average excreted 2,3-dinor-6-keto PGF level is ~100 pg/mg creatinine.3

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Technical Information
Formal Name
6-oxo-9α,11α,15S-trihydroxy-2,3-dinor-prost-13E-en-1-oic acid, sodium salt
Synonyms
  • 2,3-dinor-6-keto PGF (sodium salt)
Molecular Formula
C18H29O6 • Na
Formula Weight
364.4
Purity
≥95%
Formulation
A lyophilized powder
SMILES
O[C@@H]1[C@H](CC(CCC([O-])=O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1.[Na+]
InChI Code
InChI=1S/C18H30O6.Na/c1-2-3-4-5-12(19)6-8-14-15(17(22)11-16(14)21)10-13(20)7-9-18(23)24;/h6,8,12,14-17,19,21-22H,2-5,7,9-11H2,1H3,(H,23,24);/q;+1/p-1/b8-6+;/t12-,14+,15+,16+,17-;/m0./s1
InChI Key
CXELZMXZXOSIRU-DBAZFWCESA-M

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Fitzgerald, G.A., Lawson, J., Blair, I.A., et al. Analysis of urinary metabolites of thromboxane and prostacyclin by negative-ion chemical-ionization gas chromatography/mass spectrometry Advances in Prostaglandin, Thromboxane, and Leukotriene Research 15, 87-90 (1985).

2. Rosenkranz, B., Fischer, C., Reimann, I., et al. Identification of the major metabolite of prostacyclin and 6-ketoprostaglandin F in man Biochimica et Biophysica Acta 619, 207-213 (1980).

3. Wennmalm, Å., Benthin, G., Granström, E.F., et al. 2,3-Dinor metabolites of thromboxane A2 and prostacyclin in urine from healthy human subjects: Diurnal variation and relation to 24h excretion Clinical Science 83, 461-465 (1992).

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