A fluorescent probe for zinc detection
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Zinpyr-1

Item No. 15122

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4',5'-bis[[bis(2-pyridinylmethyl)amino]methyl]-2',7'-dichloro-3',6'-dihydroxy-spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
CAS Number
288574-78-7
Synonyms
  • ZP-1
Molecular Formula
C46H36Cl2N6O5
Formula Weight
823.7
Purity
≥90%
Emission
513-558 nm
Excitation
515-507 nm
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 0.5 mg/ml
λmax
232, 513 nm
SMILES
O=C1C(Cl)=CC(C(O2)=C1C[NH+](CC3=CC=CC=N3)CC4=NC=CC=C4)=C(C5=CC=CC=C5C([O-])=O)C6=C2C(C[NH+](CC7=CC=CC=N7)CC8=NC=CC=C8)=C([O-])C(Cl)=C6
InChi Code
InChI=1S/C46H36Cl2N6O5/c47-39-21-35-41(33-15-1-2-16-34(33)46(57)58)36-22-40(48)43(56)38(28-54(25-31-13-5-9-19-51-31)26-32-14-6-10-20-52-32)45(36)59-44(35)37(42(39)55)27-53(23-29-11-3-7-17-49-29)24-30-12-4-8-18-50-30/h1-22,55H,23-28H2,(H,57,58)
InChi Key
NKEYRLVORYSIBB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $54

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    5 mg

    $158

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    10 mg

    $290

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    Product Description

    Zinpyr-1 is a cell-permeable, fluorescein-based probe for zinc detection.1 It undergoes a shift in excitation from 515 to 507 nm with increasing zinc concentrations using an emission filter over 513-558 nm.2,1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Walkup, G.K., Burdette, S.C., Lippard, S.J., et al. A new cell-permeable fluorescent probe for Zn2+. J. Am. Chem. Soc. 122(23), 5644-5645 (2000).

    2. Burdette, S.C., Walkup, G.K., Spingler, B., et al. Fluorescent sensors for Zn2+ based on a fluorescein platform: synthesis, properties and intracellular distribution. J. Am. Chem. Soc. 123(32), 7831-7841 (2001).