A pan activator of Ras-related GTPases
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ML-099

Item No. 15176

Technical Information
Formal Name
2-[(2-phenylethyl)thio]-3-pyridinecarboxylic acid
CAS Number
496775-95-2
Synonyms
  • CID-888706
Molecular Formula
C14H13NO2S
Formula Weight
Purity
≥98%
Formulation
A crystalline solid
DMSO: 10 mg/ml
λmax
209, 269, 317 nm
SMILES
OC(C1=CC=CN=C1SCCC2=CC=CC=C2)=O
InChi Code
InChI=1S/C14H13NO2S/c16-14(17)12-7-4-9-15-13(12)18-10-8-11-5-2-1-3-6-11/h1-7,9H,8,10H2,(H,16,17)
InChi Key
UZERZZRWECLIKE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    ML-099 is a small molecule pan activator of Ras-related GTPases, activating Rac1, cell division cycle 42, Ras, and Rab-2A with EC50 values of 20, 100, 141, and 355 nM, respectively.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Surviladze, Z., Ursu, O., Miscisocia, F., et alThree small molecule pan activator families of Ras-related GTPases. 1-42 (2009).