A selective apelin receptor agonist
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Product Categories

Product Type

Small Molecule Modulators
Receptor Pharmacology
Agonists

Research Area

ML-233

Item No. 15187

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(E)-4-methyl-5-(((phenylsulfonyl)oxy)imino)-[1,1'-bi(cyclohexane)]-3,6-dien-2-one
Synonyms
  • CID-46905036
Molecular Formula
C19H21NO4S
Formula Weight
359.4
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 5 mg/ml
λmax
219, 286 nm
SMILES
CC(/C(C=C1C2CCCCC2)=N/OS(=O)(C3=CC=CC=C3)=O)=CC1=O
InChi Code
InChI=1S/C19H21NO4S/c1-14-12-19(21)17(15-8-4-2-5-9-15)13-18(14)20-24-25(22,23)16-10-6-3-7-11-16/h3,6-7,10-13,15H,2,4-5,8-9H2,1H3/b20-18+
InChi Key
RSMZOLWJZGIWOV-CZIZESTLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $50

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    5 mg

    $134

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    10 mg

    $218

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    25 mg

    $423

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    Product Description

    ML-233 is a novel APJ agonist (EC50 = 3.7 μM) that is >21-fold selective over the closely related angiotensin 1 receptor (EC50 = >79 μM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Khan, P., Maloney, P.R., Hedrick, M., et al. Functional agonists of the apelin J (APJ) receptor. 1-22 (2011).