A steroid hormone
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Aldosterone

Item No. 15273

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
11β,21-dihydroxy-3,20-dioxo-pregn-4-en-18-al
CAS Number
52-39-1
Synonyms
  • 18-Aldocorticosterone
  • NSC 73856
  • Reichstein X
Molecular Formula
C21H28O5
Formula Weight
360.4
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlEthanol:PBS(pH 7.2) (1:1): 0.2 mg/ml
λmax
240 nm
SMILES
O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C([H])=O)[C@@]3([H])CC[C@@H]4C(CO)=O)=C1
InChi Code
InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1
InChi Key
PQSUYGKTWSAVDQ-ZVIOFETBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $55

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    1 mg

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    5 mg

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    10 mg

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    Product Description

    Aldosterone is a steroid hormone secreted by the adrenal cortex and is the principle mineralocorticoid controlling sodium and potassium balance.1,2 Its primary role is to promote unidirectional salt reabsorption in epithelial tissues. Aldosterone is synthesized from cholesterol in the zona glomerulosa of the adrenal cortex and its secretion is regulated via the renin-angiotensin system.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Agarwal, M.K., and Mirshahi, M. General overview of mineralocorticoid hormone action. Pharmacol. Toxicol. 84, 273-326 (1999).

    2. Rogerson, F.M., and Fuller, P.J. Mineralocorticoid action. Steroids 65, 61-73 (2000).

    3. Lumbers, E.R. Angiotensin and aldosterone. Regul. Pept. 80, 91-100 (1999).