An antibiotic used in molecular biology
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Kanamycin A (sulfate)

Item No. 15321

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine, monosulfate
CAS Number
25389-94-0
Synonyms
  • Ophtalmokalixan
Molecular Formula
C18H36N4O11 • H2SO4
Formula Weight
582.6
Purity
≥90%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
SMILES
N[C@H]([C@H]1O)[C@H](O)[C@@H](CO)O[C@]1([H])O[C@H]([C@H]2O)[C@H](N)C[C@H](N)[C@H]2OC3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3O.O=S(O)(O)=O
InChi Code
InChI=1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18?;/m1./s1
InChi Key
OOYGSFOGFJDDHP-ULYCNMMHSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 g

    $63

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    10 g

    $86

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    25 g

    $153

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    Product Description

    Kanamycin A is a broad spectrum antibiotic isolated from a soil streptomyces (S. kanamyceticus). This aminoglycoside alters translation by prokaryotic ribosomes, resulting in bacterial cell death.1 In molecular biology, kanamycin A is used as a selective agent to isolate transformants that are expressing a kanamycin resistance gene, usually neomycin phosphotransferase (NptII/neo). This mode of selection is most commonly used in plant and mammalian biology.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Misumi, M., and Tanaka, N. Mechanism of inhibition of translocation by kanamycin and viomycin: A comparative study with fusidic acid. Biochem. Biophys. Res. Commun. 92(2), 647-654 (1980).