An isoprostane found in human semen
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8-iso Prostaglandin F1α

Item No. 15350

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(8β)-9α,11α,15S-trihydroxy-prost-13E-en-1-oic acid
CAS Number
26771-96-0
Synonyms
  • 8-epi PGF1α
  • 8-iso PGF1α
Molecular Formula
C20H36O5
Formula Weight
356.5
Purity
≥99%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 50 mg/mlDMSO: 50 mg/mlEthanol: 50 mg/mlPBS (pH 7.2): 1 mg/ml
SMILES
O[C@@H]1[C@@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1
InChi Code
InChI=1S/C20H36O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-19,21-23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16-,17+,18-,19+/m0/s1
InChi Key
DZUXGQBLFALXCR-PUCCXBQTSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    8-iso Prostaglandin F1α (8-iso PGF1α) is an isoprostane that was first identified in human semen.1 It is a member of the isoprostane family, which are eicosanoids of non-cyclooxygenase origin. 8-iso PGF1α is present along with its 19-hydroxy congener at 5-10 µg/ml of seminal plasma.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Svanborg, K., Bygdeman, M., and Eneroth, P. The F and 19-hydroxy F prostaglandins and their 8β-isomers in human seminal plasma: Data on chromatography and mass spectrometry. Biomed. Mass Spectrom. 10(9), 495-498 (1983).

    2. Taylor, P.L. The 8-isoprostaglandins: Evidence for eight compounds in human semen. Prostaglandins 17(2), 259-267 (1979).