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Clencyclohexerol

Item No. 15365

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-amino-3,5-dichloro-α-[[(4-hydroxycyclohexyl)amino]methyl]-benzenemethanol
CAS Number
157877-79-7
Molecular Formula
C14H20Cl2N2O2
Formula Weight
319.2
Purity
≥90%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 2 mg/ml
λmax
211, 248 nm
SMILES
OC1CCC(NCC(O)C2=CC(Cl)=C(N)C(Cl)=C2)CC1
InChi Code
InChI=1S/C14H20Cl2N2O2/c15-11-5-8(6-12(16)14(11)17)13(20)7-18-9-1-3-10(19)4-2-9/h5-6,9-10,13,18-20H,1-4,7,17H2
InChi Key
DKFLKXDTRUWFDL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Clencyclohexerol is an analog of clenbuterol (Item No. 14985). β-Adrenoceptor agonists, including clenbuterol, modulate protein synthesis and degradation and have therapeutic potential in muscle wasting disorders.1 However, they are abused to stimulate muscle mass production, both in food-producing animals and in humans.2,3 Importantly, β-adrenoceptor agonists have deleterious cardiovascular side effects when used systemically and at high concentrations.1 The physiological, cardiovascular, and toxicological properties of clencyclohexerol have not been evaluated. This product is intended for forensic and research purposes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ryall, J.G., and Lynch, G.S. The potential and the pitfalls of β-adrenoceptor agonists for the management of skeletal muscle wasting. Pharmacol. Ther. 120(3), 219-232 (2008).

    2. Salquèbre, G., Bresson, M., Villian, M., et al. Clenbuterol determination in calf hair by UPLC-MS-MS: Case report of a fraudulent use for cattle growth. J. Anal. Toxicol. 31(2), 114-118 (2007).

    3. Kanayama, G., and Pope, H.G., Jr. Illicit use of androgens and other hormones: Recent advances. Curr. Opin. Endrocrinol. Diabetes Obes. 19(3), 211-219 (2012).