A selective inhibitor of peptidoglycan glycosyltransferases
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Moenomycin Complex

Item No. 15506

Technical Information
CAS Number
11015-37-5
Synonyms
  • Bambermycin
  • Flavomycin
  • Flavophospholipol
  • Gainpro
Molecular Formula
C69H108N5O34P (for A)
Formula Weight
Purity
≥95%
A solid
DMF: SolubleDMSO: SolubleEthanol: SolubleMethanol: Soluble
SMILES
O[C@H]1[C@@H](O)[C@H](O)[C@](O[C@H]2[C@H](C)O[C@@](O[C@H]3[C@H](C[R3])O[C@@](O[C@H]4[C@H](OC(C)=O)[C@]([R2])([R1])[C@H](C(N)=O)O[C@H]4OP(OC[C@@H](C(O)=O)OC/C=C(CC/C=C\C(C)(C)CCC(C/C=C(C)/CC/C=C(C)/C)=C)/C)(O)=O)([H])[C@@H](NC(C)=O)[C@@H]3O)([H])[C@@H](NC(C)=O)[C@@H]2O)([H])O[C@H]1C(NC5=C(O)CCC5=O)=O
Origin
Bacterium/Streptomyces sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Moenomycin complex is a mixture of moenomycins A, A12, C1, C3 and C4, which are antibiotics isolated from several strains of Streptomyces that directly inhibit bacterial peptidoglycan glycosyltransferases.1 The minimal inhibitory concentration of moenomycin A against various Gram-positive bacteria ranges from 1-100 nM.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ostash, B., and Walker, S. Moenomycin family antibiotics: Chemical synthesis, biosynthesis, biological activity. Nat. Prod. Rep. 27(11), 1594-1617 (2010).