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FUB-144

Item No. 15537

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • FUB-UR-144
Technical Information
Formal Name
[1-[(4-fluorophenyl)methyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-methanone
CAS Number
2185863-15-2
Molecular Formula
C23H24FNO
Formula Weight
349.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMF:PBS (pH 7.2) (1:2): 0.3 mg/mlDMSO: 25 mg/mlEthanol: 10 mg/ml
λmax
212, 245, 302 nm
SMILES
O=C(C1C(C)(C)C1(C)C)C2=CN(CC3=CC=C(F)C=C3)C4=C2C=CC=C4
InChi Code
InChI=1S/C23H24FNO/c1-22(2)21(23(22,3)4)20(26)18-14-25(19-8-6-5-7-17(18)19)13-15-9-11-16(24)12-10-15/h5-12,14,21H,13H2,1-4H3
InChi Key
UXOFEILQVZFLRH-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $90

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    5 mg

    $349

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    10 mg

    $488

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    Cayman Chemical
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    Product Description

    XLR11 (Item No. 11565) is a synthetic cannabinoid (CB) featuring a tetramethylcyclopropyl group, which reportedly confers selectivity for the peripheral CB2 receptor over the central CB1 receptor.1 It also features an N-(5-fluoropentyl) chain, which increases binding to both CB receptors.2 FUB-144 is a derivative of XLR11 in which the 5-fluoropentyl side chain is replaced by a 4-fluorobenzyl group, a functional group also found in the indazole-based synthetic cannabinoids AB-FUBINACA (Item No. 14292) and ADB-FUBINACA (Item No. 14039).3,4 The physiological and toxicological properties of this compound are not known. FUB-144 is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Frost, J.M., Dart, M.J., Tietje, K.R., et al. Indol-3-ylcycloalkyl ketones: Effects of N1 substituted indole side chain variations on CB2 cannabinoid receptor activity. J. Med. Chem. 53(1), 295-315 (2010).

    2. Makriyannis, A., and Deng, H. Cannabimimetic indole derivatives. US7241799B2, (2001).

    3. Uchiyama, N., Matsuda, S., Wakana, D., et al. New cannabimimetic indazole derivatives, N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (AB-PINACA) and N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (AB-FUBINACA) identified as designer drugs in illegal products. Forensic Toxicol. 31(1), 93-100 (2013).

    4. Buchler, I.P., Hayes, M.J., Hedge, S.G., et al. Indazole derivatives. 1-283 (2009).

    Product Citations

    Al-Matrouk, A., and Orabi, K.Y. Identification and chemical structure elucidation of synthetic cannabinoids samples seized in Kuwait during 2019-2023 using GC-MS and NMR spectroscopy. Forensic Sci. Res. 10(2), owae026 (2025).