A β-adrenergic agonist
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Labeled Version(s)
28903Cimaterol-d7
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Cimaterol

Item No. 15613

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-amino-5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-benzonitrile
CAS Number
54239-37-1
Synonyms
  • Cimaterolum
Molecular Formula
C12H17N3O
Formula Weight
219.3
Purity
≥99%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: 100 mMEthanol: 50 mM
λmax
218, 253 nm
SMILES
NC1=CC=C(C(O)CNC(C)C)C=C1C#N
InChi Code
InChI=1S/C12H17N3O/c1-8(2)15-7-12(16)9-3-4-11(14)10(5-9)6-13/h3-5,8,12,15-16H,7,14H2,1-2H3
InChi Key
BUXRLJCGHZZYNE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

    $117

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    50 mg

    $484

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    Product Description

    Cimaterol is a potent agonist of β-adrenergic receptors (pEC50 = 8.13, 8.78, and 6.62 for human β1, β2, and β3, respectively).1 Formulations containing cimoterol have been used in farmed animals (swine, fowl, etc.) to increase carcass mass and to alter muscle and fat deposition.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Mistry, S.N., Baker, J.G., Fischer, P.M., et al. Synthesis and in vitro and in vivo characterization of highly β1-selective β-adrenoceptor partial agonists. J. Med. Chem. 56(10), 3852-3865 (2013).

    2. Jones, R.W., Easter, R.A., McKeith, F.K., et al. Effect of the β-adrenergic agonist cimaterol (CL 263,780) on the growth and carcass characteristics of finishing swine. J. Anim. Sci. 61(4), 905-913 (1985).

    3. Byrem, T.M., Beermann, D.H., and Robinson, T.F. The β-agonist cimaterol directly enhances chronic protein accretion in skeletal muscle. J. Anim. Sci. 76(4), 988-998 (1998).