The initial metabolite of PGF1α
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15-keto Prostaglandin F1α

Item No. 15710

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9α,11α-dihydroxy-15-oxo-prost-13E-en-1-oic acid
CAS Number
21562-58-3
Synonyms
  • 15-keto PGF1α
Molecular Formula
C20H34O5
Formula Weight
354.5
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: >50 mg/mlDMSO: >50 mg/mlEthanol: >75 mg/mlPBS (pH 7.2): >2 mg/ml
λmax
232 nm
SMILES
O[C@@H]1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/C(CCCCC)=O)[C@H](O)C1
InChi Code
InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,16-19,22-23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t16-,17-,18+,19-/m1/s1
InChi Key
QPXXPLNAYDQELM-QNXXGYPUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    5 mg

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    10 mg

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    Product Description

    15-keto Prostaglandin F1α (15-keto PGF1α) is the initial metabolite of PGF1α via 15-hydroxy PGDH. In mammals, oxidation of C-15 markedly attenuates receptor binding and activity. In fish, the 15-keto compounds serve as post-ovulatory pheromones and are more active than the parent prostaglandins.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sorensen, P.W., Hara, T.J., Goetz, F.W., et al. F prostaglandins function as potent olfactory stimulants that comprise the postovulatory female sex pheromone in goldfish. Biol. Reprod. 39(5), 1039-1050 (1988).