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25B-NBOMe (hydrochloride) (exempt preparation)

Item No. 15723

Exempt Product (US)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 2C-B-NBOMe
Technical Information
Formal Name
4-bromo-2,5-dimethoxy-N-[(2-methoxyphenyl)methyl]-benzeneethanamine, monohydrochloride
CAS Number
1539266-15-3
Molecular Formula
C18H22BrNO3 • HCl
Formula Weight
416.7
Purity
≥98%
Formulation
A 1 mg/ml solution in methanol
λmax
204, 282, 296 nm
SMILES
BrC1=C(OC)C=C(CCNCC2=C(OC)C=CC=C2)C(OC)=C1.Cl
InChi Code
InChI=1S/C18H22BrNO3.ClH/c1-21-16-7-5-4-6-14(16)12-20-9-8-13-10-18(23-3)15(19)11-17(13)22-2;/h4-7,10-11,20H,8-9,12H2,1-3H3;1H
InChi Key
HUHVUTZPPOFALF-UHFFFAOYSA-N
Regulatory Information
DEA Exempt Notification
This product is a DEA exempt preparation of a scheduled compound - does not require DEA Controlled Substance registration or DEA 222 form. For alternate sizes please contact sales.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $69

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    Product Description

    2C-B is a hallucinogenic designer drug which potently activates the serotonin receptor 5-HT2C (pEC50 = 6.8 for arachidonic acid release).1 25B-NBOMe is a derivative of 2C-B, characterized by the addition of a benzyl-methoxy (BOMe) group to the amine. This N-(2-methoxybenzyl) addition significantly increases the affinity (Ki = 1.01 nM) and activity (ED50 = 0.51 nM) at the serotonin receptor 5-HT2A.2 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Moya, P.R., Berg, K.A., Gutiérrez-Hernandez, M.A., et al. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors. J. Pharmacol. Exp. Ther. 321(3), 1054-1061 (2007).

    2. Ettrup, A., Hansen, M., Santini, M.A., et al. Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT2A agonist PET tracers. Eur. J. Nucl. Med. Mol. Imaging 38(4), 681-693 (2011).