An analgesic and anti-inflammatory compound
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Analytical Standard(s)
32992Aminophenazone
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Product Categories

Product Type

Biochemicals

Research Area

Immunology & Inflammation
Neuroscience
Pain Research

Aminophenazone

Item No. 15770

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-(dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one
CAS Number
58-15-1
Synonyms
  • 4-Dimethylaminoantipyrine
  • Aminopyrine
  • NSC 4993
Molecular Formula
C13H17N3O
Formula Weight
231.3
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 5 mg/mlEthanol: 25 mg/mlEthanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
λmax
238, 271 nm
SMILES
CN(C)C1=C(C)N(C)N(C2=CC=CC=C2)C1=O
InChi Code
InChI=1S/C13H17N3O/c1-10-12(14(2)3)13(17)16(15(10)4)11-8-6-5-7-9-11/h5-9H,1-4H3
InChi Key
RMMXTBMQSGEXHJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    10 g

    $37

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    25 g

    $81

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    50 g

    $151

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    100 g

    $229

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    Product Description

    Aminophenazone is an analgesic and anti-inflammatory compound.1 It decreases acetic acid-induced writhing in mice (ED50 = 46 mg/kg, s.c.) and reduces inflammation in a rat model of paw edema when administered at a dose of 48.2 mg/kg. Formulations containing aminophenazone have previously been used in the treatment of pain.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Takaya, M., Sato, M., Terashima, K., et al. A new nonsteroidal analgesic-antiinflammatory agent. Synthesis and activity of 4-ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone and related compounds. J. Med. Chem. 22(1), 53-58 (1979).