An inhibitor of LTA4 hydrolase
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

ARM1

Item No. 15865

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[4-(phenylmethyl)phenyl]-2-thiazolamine
CAS Number
68729-05-5
Molecular Formula
C16H16N2S
Formula Weight
268.4
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 15 mg/mlDMF:PBS(pH 7.2)(1:6): 0.1 mg/mlDMSO: 10 mg/mlEthanol: 1mg/ml
λmax
236, 285, 344 nm
SMILES
NC(N1)=SC=C1C(C=C2)=CC=C2CC3=CC=CC=C3
InChi Code
InChI=1S/C16H16N2S/c17-16-18-15(11-19-16)14-8-6-13(7-9-14)10-12-4-2-1-3-5-12/h1-9,11,18-19H,10,17H2
InChi Key
CEXYUVBVAHGQJI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $69

    Add

    10 mg

    $127

    Add

    50 mg

    $525

    Add

    100 mg

    $918

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    ARM1 is a thiazolamine that inhibits LTB4 synthesis in human neutrophils (IC50 = ~0.5 µM) and conversion of LTA4 to LTB4 by purified LTA4 hydrolase (Ki = 2.3 µM).1 ARM1 does not significantly affect the hydrolysis of Pro-Gly-Pro by LTA4 hydrolase.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Stsiapanava, A., Olsson, U., Wan, M., et al. Binding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitor. Proc. Natl. Acad. Sci. USA 111(11), 4227-4232 (2014).