A β-lactam antibiotic
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Moxalactam (sodium salt)

Item No. 15869

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(6R,7R)-7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, disodium salt
CAS Number
64953-12-4
Synonyms
  • Antibiotic 6059S
  • Latamoxef
  • LY 127935
Molecular Formula
C20H18N6O9S • 2Na
Formula Weight
564.4
Purity
≥85% (mixture of isomers)
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 5 mg/mlWater: 50 mg/ml
λmax
229, 271 nm
SMILES
OC1=CC=C([C@@H](C([O-])=O)C(N[C@@]2(OC)[C@](OCC(CSC3=NN=NN3C)=C4C([O-])=O)([H])N4C2=O)=O)C=C1.[Na+].[Na+]
InChi Code
InChI=1S/C20H20N6O9S.2Na/c1-25-19(22-23-24-25)36-8-10-7-35-18-20(34-2,17(33)26(18)13(10)16(31)32)21-14(28)12(15(29)30)9-3-5-11(27)6-4-9;;/h3-6,12,18,27H,7-8H2,1-2H3,(H,21,28)(H,29,30)(H,31,32);;/q;2*+1/p-2/t12-,18-,20+;;/m1../s1
InChi Key
GRIXGZQULWMCLU-GDUWRUPCSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Cayman Chemical
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    Product Description

    Moxalactam is a β-lactam antibiotic in the cephalosporin class. It is classified as an oxacephem, as oxygen replaces sulfur in position one of the dihydrothiazolidine ring.1 While moxalactam inhibits most commonly occurring gram positive, gram negative, and anaerobic bacteria, it is ineffective against methicillin-resistant S. aureus and Enterococci.1 In certain situations, this antibiotic impairs normal hemostasis, most commonly manifested as a prolonged bleeding time.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Neu, H.C. The in vitro activity, human pharmacology, and clinical effectiveness of new β-lactam antibiotics. Annu. Rev. Pharmacol. Toxicol. 22, 599-642 (1982).

    2. Sattler, F.R., Weitekamp, M.R., and Ballard, J.O. Potential for bleeding with the new beta-lactam antibiotics. Ann. Intern. Med. 105(6), 924-931 (1986).