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Isomer(s)
31185AFUB7AICA
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AKB48 N-(4-fluorobenzyl) analog

Item No. 15937

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • AFB-48
  • ​AFUBINACA
  • FUB-AKB48
  • FUB-APINACA
Technical Information
Formal Name
1-[(4-fluorophenyl)methyl]-N-tricyclo[3.3.1.13,7]dec-1-yl-1H-indazole-3-carboxamide
CAS Number
2180933-90-6
Molecular Formula
C25H26FN3O
Formula Weight
403.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 5 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2) (1:2): 0.3 mg/ml
λmax
210, 302 nm
SMILES
O=C(NC1(C[C@H]2C3)C[C@H]3C[C@H](C2)C1)C4=NN(CC5=CC=C(F)C=C5)C6=C4C=CC=C6
InChi Code
InChI=1S/C25H26FN3O/c26-20-7-5-16(6-8-20)15-29-22-4-2-1-3-21(22)23(28-29)24(30)27-25-12-17-9-18(13-25)11-19(10-17)14-25/h1-8,17-19H,9-15H2,(H,27,30)/t17-,18+,19-,25?
InChi Key
MWBHSNBPUSKVDD-LPSAYFBNSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    AKB48 (Item No. ISO00060) is a pentyl indazole with structural similarity to the synthetic cannabinoids (CBs) JWH 018 adamantyl carboxamide (Item No. 9001193) and STS-135 (Item No. 11564), which have been sold for recreational use.1 Generally, quinolones with adamantyl-carboxamide moieties display high affinity for the peripheral cannabinoid (CB2) receptor but greatly reduced affinity for the central cannabinoid (CB1) receptor.2 AKB48 N-(4-fluorobenzyl) analog is an AKB48 derivative in which the pentyl chain has been replaced with a 4-fluorobenzyl group in order to mimic a structural feature of the potent CB1 modulator AB-FUBINACA (Item No. 14039). The physiological properties of this compound are not known. AKB48 N-(4-fluorobenzyl) analog is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1.  AKB48 (APINACA) and 5F-AKB48 (5F-APINACA). (2013).

    2. Pasquini, S., De Rosa, M., Pedani, V., et al. Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice. J. Med. Chem. 54(15), 5444-5453 (2011).