An Analytical Reference Standard
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Certified Reference Material(s)
42198Delorazepam (CRM)
Labeled Version(s)
42199Delorazepam-13C2-d4 (CRM)
Parent Compound(s)
15554Diclazepam 28623Diclazepam (CRM)
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Delorazepam

Item No. 15938

Restricted Product (Schedule IV)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Chlordesmethyldiazepam
  • NSC 169895
  • Ro 5-3027
Technical Information
Formal Name
7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
CAS Number
2894-67-9
Molecular Formula
C15H10Cl2N2O
Formula Weight
305.1
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:1): 0.5 mg/mlEthanol: 10 mg/ml
λmax
227, 319 nm
SMILES
ClC1=CC(C(C2=C(Cl)C=CC=C2)=NC3)=C(C=C1)NC3=O
InChi Code
InChI=1S/C15H10Cl2N2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)
InChi Key
CHIFCDOIPRCHCF-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
IV
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Delorazepam is a benzodiazepine with anxiolytic effects.1 It is a metabolite of the designer drug diclazepam that can be detected in either the serum or urine.2 Delorazepam can also be produced by enzymatic treatment of lorazepam with β-glucuronidase.3 This compound is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Paradiso, L., and Rapisarda, V. The psychosedative effect of chlordesmethyldiazepam on anxiety states in neurotic and psychotic inpatients. Clin. Ther. 3(3), 194-199 (1980).

    2. Moosmann, B., Bisel, P., and Auwärter, V. Characterization of the designer benzodiazepine diclazepam and preliminary data on its metabolism and pharmacokinetics. Drug Test Anal. 6(7-8), 757-763 (2014).

    3. Fu, S., Molnar, A., Bowron, P., et al. Reduction of temazepam to diazepam and lorazepam to delorazepam during enzymatic hydrolysis. Anal. Bioanal. Chem. 400(1), 153-164 (2011).