For immunochemical detection of LTA4 hydrolase
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Leukotriene A4 Hydrolase Polyclonal Antibody

Item No. 160250

Technical Information
Synonyms
  • LTA4 Hydrolase
Immunogen
Recombinant human LTA4 hydrolase{969,4145}
100 µg of protein A-purified polyclonal antibody
Storage Buffer
PBS, pH 7.2, with 50% glycerol, 0.5 mg/ml BSA, and 0.02% sodium azide
Host
Rabbit
Applications
IHC and WB
Species Reactivity
(+) Human
UniProt Accession №
P09960
Origin
Animal/Rabbit
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Leukotriene A4 hydrolase (LTA4 hydrolase) has been cloned from a variety of species including human, rat, and guinea pig.1,2,3,4 These species exhibit ~90% homology at the amino acid level. Human LTA4 hydrolase has a calculated molecular mass of 69 kDa based on the deduced amino acid sequence.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Funk, C.D., Rådmark, O., Fu, J.Y., et alMolecular cloning and amino acid sequence of leukotriene A4 hydrolase. Proc. Natl. Acad. Sci. USA 84, 6677-6681 (1987).

    2. Minami, M., Ohno, S., Kawasaki, H., et alMolecular cloning of a cDNA coding for human leukotriene A4 hydrolase. Complete primary structure of an enzyme involved in eicosanoid synthesis. The Journal of Biological Chemisty 262, 13873-13876 (1987).

    3. Makita, N., Funk, C.D., Imai, E., et alMolecular cloning and functional expression of rat leukotriene A4 hydrolase using the polymerase chain reaction. FEBS Lett. 299, 273-277 (1992).

    4. Minami, M., Mutoh, H., Ohishi, N., et alAmino-acid sequence and tissue distribution of guinea-pig leukotriene A4 hydrolase. Gene 161, 249-251 (1995).

    Product Citations

    Zhao, S., Yao, K., Li, D., et alInhibition of LTA4H by bestatin in human and mouse colorectal cancer. EBioMedicine 44, 361-374 (2019).