An anti-Leishmania antimony derivative
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Sodium Stibogluconate

Item No. 16038

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,4:2',4'-O-(oxydistibylidyne)bis-D-gluconic acid, trisodium salt, nonahydrate
CAS Number
16037-91-5
Synonyms
  • Antimony Sodium Gluconate
Molecular Formula
C12H17O17Sb2 • 3Na [9H2O]
Formula Weight
907.9
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
λmax
266, 321 nm
SMILES
OC[C@@H](O)[C@]1([H])[C@H](O)[C@H](C([O-])=O)O[Sb](O[Sb]2(O[C@@]([C@H](O)CO)([H])[C@H](O)[C@H](C([O-])=O)O2)=O)([O-])O1.[Na+].[Na+].[Na+].O.O.O.O.O.O.O.O.O
InChi Code
InChI=1S/2C6H10O7.3Na.9H2O.3O.2Sb/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;;;;;;;;;;;;;;;;;/h2*2-5,7-8,10H,1H2,(H,12,13);;;;9*1H2;;;;;/q2*-2;3*+1;;;;;;;;;;;;-1;2*+2/p-2/t2*2-,3-,4+,5-;;;;;;;;;;;;;;;;;/m11................./s1
InChi Key
XGOCPLVXEKPVLV-UZVLBLASSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Sodium stibogluconate is a pentavalent antimony derivative that is highly active against Leishmania amastigotes in macrophages.1 Sodium stibogluconate has diverse effects on both this intracellular parasite and its host cell.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Roberts, W.L., and Rainey, P.M. Antileishmanial activity of sodium stibogluconate fractions. Antimicrob. Agents Chemother. 37(9), 1842-1846 (1993).

    2. Frézard, F., Demicheli, C., and Ribeiro, R.R. Pentavalent antimonials: New perspectives for old drugs. Molecules 14(7), 2317-2336 (2009).

    3. Singh, N., Kumar, M., and Singh, R.K. Leishmaniasis: Current status of available drugs and new potential drug targets. Asian Pac. J. Trop. Med. 5(6), 485-497 (2012).