For immunochemical detection of PGIS
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Prostaglandin I Synthase Monoclonal Antibody (Clone isn-1)

Item No. 160630

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • PGI Synthase
  • PGIS
  • Prostacyclin Synthase
Immunogen
bovine lung PGIS
Clone Designation
isn-1
Formulation (Request formulation change)
250 µg of protein A-purified monoclonal antibody
Storage Buffer
TBS, pH 7.4, when reconstituted in 250 µl of deionized water (1 mg/ml)
Host
Mouse
Isotype
IgG1
Applications
IP and IHC; WB not recommended
Species Reactivity
(+) Bovine PGIS(+) Guinea pig PGIS(+) Mouse PGIS(+) Ovine PGIS(+) Rabbit PGIS(+) Rat PGIS
UniProt Accession №
O62698
Origin
Animal/Mouse
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    1 ea (250 µg)

    $347

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    Product Description

    PGI synthase (PGIS) catalyzes the conversion of PGH2 to PGI2 (prostacyclin). Human lung PGIS is a 56 kDa protein. The cloned bovine and human enzymes contain 500 amino acids and have a calculated molecular mass of 56,629 and 57,103, respectively.1,2,3 There is 88% homology between human and bovine PGIS.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Miyata, A., Hara, S., Yokoyama, C., et al. Molecular cloning and expression of human prostacyclin synthase. Biochem. Biophys. Res. Commun. 200(3), 1728-1734 (1994).

    2. Pereira, B., Wu, K.K., and Wang, L.H. Molecular cloning and characterization of bovine prostacyclin synthase. Biochem. Biophys. Res. Commun. 203(1), 59-66 (1994).

    3. Hara, S., Miyata, A., Yokoyama, C., et al. Isolation and molecular cloning of prostacyclin synthase from bovine endothelial cells. The Journal of Biological Chemisty 269(31), 19897-19903 (1994).