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M-144

Item No. 16084

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • XLR11 2-methylindole analog
Technical Information
Formal Name
[1-(5-fluoropentyl)-2-methyl-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-methanone
CAS Number
2180924-19-8
Molecular Formula
C22H30FNO
Formula Weight
343.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2) (1:4): 0.2 mg/ml
λmax
220, 250, 305 nm
SMILES
O=C(C1C(C)(C)C1(C)C)C2=C(C)N(CCCCCF)C3=C2C=CC=C3
InChi Code
InChI=1S/C22H30FNO/c1-15-18(19(25)20-21(2,3)22(20,4)5)16-11-7-8-12-17(16)24(15)14-10-6-9-13-23/h7-8,11-12,20H,6,9-10,13-14H2,1-5H3
InChi Key
SVBIXYNVVDXJGW-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    UR-144 (Item No. 11502) is a potent synthetic cannabinoid (CB) which preferentially binds the peripheral cannabinoid (CB2) receptor (Ki = 1.8 nM) over the central cannabinoid (CB1) receptor (Ki = 150 nM).1 M-144 differs from UR-144 by having a fluorine atom on the terminal carbon of the alkyl group as well as a methyl group attached to the C2 carbon of the indole. The biological activities of this compound have not been characterized. This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Frost, J.M., Dart, M.J., Tietje, K.R., et al. Indol-3-ylcycloalkyl ketones: Effects of N1 substituted indole side chain variations on CB2 cannabinoid receptor activity. J. Med. Chem. 53(1), 295-315 (2010).