A cephalosporin antibiotic
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Cefoperazone (sodium salt)

Item No. 16113

Technical Information
Formal Name
(6R,7R)-7-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt
CAS Number
62893-20-3
Synonyms
  • Cefoneg
  • Cefosint
  • CP 52,640-2
  • Perocef
Molecular Formula
C25H26N9O8S2 • Na
Formula Weight
Purity
≥95%
A crystalline solid
DMF: 15 mg/mlDMSO: 20 mg/mlPBS (pH 7.2): 3 mg/ml
λmax
229, 268 nm
SMILES
CCN(CCN(C(N[C@H](C1=CC=C(O)C=C1)C(N[C@@H]2C(N3[C@]2([H])SCC(CSC4=NN=NN4C)=C3C([O-])=O)=O)=O)=O)C5=O)C5=O.[Na+]
InChi Code
InChI=1S/C25H27N9O8S2.Na/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2;/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41);/q;+1/p-1/t15-,16-,22-;/
InChi Key
NCFTXMQPRQZFMZ-WERGMSTESA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Cefoperazone is a cephalosporin antibiotic that is active in vitro against most Gram-positive and Gram-negative bacteria, including β-lactamase strains (3-4 µg/ml inhibits 90% of S. aureus growth).1 It has been studied in the treatment of upper and lower respiratory tract infections, urinary tract infections, gynecological infections, skin infections, as well as bacteremia.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Neu, H.C. The in vitro activity, human pharmacology, and clinical effectiveness of new β-lactam antibiotics. Annu. Rev. Pharmacol. Toxicol. 22, 599-642 (1982).