An anion transport inhibitor
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Product Type

Small Molecule Modulators
Ion Channel Modulators
Blockers

Research Area

DIDS (sodium salt)

Item No. 16125

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,2'-(1,2-ethenediyl)bis[5-isothiocyanato-benzenesulfonic acid], disodium salt
CAS Number
67483-13-0
Synonyms
  • 4,4'-Diisothiocyanato-2.2'-stilbenedisulfonic acid
  • MDL 101114ZA
Molecular Formula
C16H8N2O6S4 • 2Na
Formula Weight
498.5
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 20 mg/mlPBS (pH 7.2): 1 mg/ml
λmax
344, 353 nm
SMILES
[O-]S(C1=CC(N=C=S)=CC=C1C=CC2=C(S([O-])(=O)=O)C=C(N=C=S)C=C2)(=O)=O.[Na+].[Na+]
InChi Code
InChI=1S/C16H10N2O6S4.2Na/c19-27(20,21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,23)24;;/h1-8H,(H,19,20,21)(H,22,23,24);;/q;2*+1/p-2
InChi Key
GEPAYBXVXXBSKP-UHFFFAOYSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $58

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    50 mg

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    100 mg

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    250 mg

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    Product Description

    DIDS is a stilbene sulfonate that inhibits anionic transport. It has been used to inhibit Cl- uptake through plasma membrane-localized Cl- channels in order to study chloride transport.1 It also effectively inhibits various sodium-coupled bicarbonate transporters.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Pusch, M., Zifarelli, G., Murgia, A., et al. Channel or transporter? The CLC saga continues. Exp. Physiol. 91(1), 149-152 (2006).

    2. Boron, W.F. Sodium-coupled bicarbonate transporters. JOP 2(4 Suppl), 176-181 (2001).